$49.99
Note: Shipped In Freeze Dried Lyophilized Form – Requires Reconstitution
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ARA-290, also known as cibinetide, is a synthetic peptide derivative of erythropoietin (EPO) designed to selectively target the innate repair receptor (IRR) without activating the erythropoietic pathway. Structurally, it is an 11–amino acid peptide modeled from the B-helix region of EPO, engineered to retain tissue-protective properties while avoiding stimulation of red blood cell production.
In research contexts, ARA-290 is studied for its interaction with the IRR, a heteromeric complex composed of the erythropoietin receptor (EPOR) and the β-common receptor (CD131). This receptor complex has been implicated in cellular signaling pathways related to anti-inflammatory responses, tissue protection, and repair mechanisms.
Due to its targeted receptor activity and short peptide structure, ARA-290 has attracted attention in preclinical and clinical studies exploring metabolic regulation, immune modulation, and neuroprotection.
