TB-500 is a synthetic peptide modeled after a functional region of thymosin beta-4, consisting of 43 amino acids. It is studied for its role in tissue remodeling, cellular migration, and actin regulation. In vitro research focuses on TB-500’s effects on angiogenesis, inflammatory response modulation, and wound repair signaling. The peptide is of particular interest in models involving epithelial and connective tissue dynamics due to its influence on cytoskeletal reorganization and cell motility.